Product overview
Description Anti-ID2 rabbit polyclonal antibody
Applications ELISA, IHC
Immunogen Synthetic peptide of human ID2
Reactivity Human, Mouse, Rat
Content 0.4 mg/ml
Host species Rabbit
Ig class Immunogen-specific rabbit IgG
Purification Antigen affinity purification
Target information
Symbol ID2
Full name inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
Synonyms GIG8; ID2A; ID2H; bHLHb26
Swissprot Q02363
Target Background
The protein encoded by this gene belongs to the inhibitor of DNA binding family, members of which are transcriptional regulators that contain a helix-loop-helix (HLH) domain but not a basic domain. Members of the inhibitor of DNA binding family inhibit the functions of basic helix-loop-helix transcription factors in a dominant-negative manner by suppressing their heterodimerization partners through the HLH domains. This protein may play a role in negatively regulating cell differentiation. A pseudogene of this gene is located on chromosome 3.