- ￥279 - 5600
- MedChemExpress(MCE)
- 美国
- HY-13503
- 2025年12月05日
企业认证
相关产品推荐更多 >
万千商家帮你免费找货
0 人在求购买到急需产品
- 详细信息
- 技术资料
- 保存条件：
Powder: -20°C, 3 years.In solvent: -80°C, 6 months; -20°C, 1 month.
- 英文名：
Epo A
- 库存：
货期：1-2天
- 供应商：
MedChemExpress LLC
- CAS号：
152044-53-6
- 规格：
10 mM * 1 mL/1 mg/5 mg/10 mg/25 mg/50 mg/100 mg/200 mg
| 规格： | 10 mM * 1 mL | 产品价格： | ￥608.0 |
|---|---|---|---|
| 规格： | 1 mg | 产品价格： | ￥279.0 |
| 规格： | 5 mg | 产品价格： | ￥560.0 |
| 规格： | 10 mg | 产品价格： | ￥885.0 |
| 规格： | 25 mg | 产品价格： | ￥1788.0 |
| 规格： | 50 mg | 产品价格： | ￥2738.0 |
| 规格： | 100 mg | 产品价格： | ￥4113.0 |
| 规格： | 200 mg | 产品价格： | ￥5600.0 |
MCE 的所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务。
Epothilone A
CAS No. : 152044-53-6
MCE 国际站：Epothilone A
产品活性：Epothilone A 是紫杉醇和管蛋白 (tubulin) 聚合物结合的竞争性抑制剂，其 Ki 值为 0.6-1.4 μM。
研究领域：Cell Cycle/DNA Damage | Cytoskeleton | Apoptosis
作用靶点：Microtubule/Tubulin | Apoptosis
In Vitro: Epothilone A is a competitive inhibitor of the binding of [3H] paclitaxel to tubulin polymers. The apparent Ki value for Epothilone A is 1.4 μM by Hanes analysis and 0.6 μM by Dixon analysis. Epothilone A, is noted to be highly cytotoxic (IC50=0.05 μM) in vitro when applied to the human T-24 bladder carcinoma cell line. The binding affinity of Epothilone A to tubulin is of the same order of magnitude as the binding affinity of paclitaxel to tubulin based on competition assays. The IC50 for displacement of 100 nM of (3H) paclitaxel from the tubulin binding site is 3.6 μM for paclitaxel, 2.3 μM for Epothilone A, and 3.3 μM for patupilone.
相关产品：Covalent Screening Library Plus | Natural Product Library Plus | Bioactive Compound Library Plus | Apoptosis Compound Library | Cell Cycle/DNA Damage Compound Library | Natural Product Library | Anti-Cancer Compound Library | Anti-Aging Compound Library | Covalent Screening Library | Lipid Compound Library | Cytoskeleton Compound Library | Anti-Lung Cancer Compound Library | Microbial Metabolite Library | Anti-Cancer Natural Product Library | Protein-protein Interaction Inhibitor Library | Cysteine Targeted Covalent Library | Cell Death Library | MG-132 | Doxorubicin hydrochloride | Bafilomycin A1 | LY294002 | Tamoxifen | Paclitaxel | Y-27632 | Acetylcysteine | Angiotensin II human | 2-Deoxy-D-glucose | Staurosporine | SB-431542 | Actinomycin D | Deferoxamine mesylate | Bortezomib | 5-Fluorouracil | Trametinib | Sorafenib | Oxaliplatin | Gemcitabine | Temozolomide | Rotenone | Mdivi-1 | Elesclomol | Ruxolitinib | Decitabine | SP600125 | MK-2206 dihydrochloride | Etoposide | Monomethyl auristatin E
热门产品线：重组蛋白 | 化合物库 | 天然产物 | 荧光染料 | PROTAC | 同位素标记物
Trending products：Recombinant Proteins | Bioactive Screening Libraries | Natural Products | Dye Reagents | PROTAC | Isotope-Labeled Compounds
风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。
技术资料暂无技术资料 索取技术资料
