Anti-NPPB antibody

Anti-NPPB antibody

Cat. No.     JC160131        
Package    25 μl/100 μl/200 μl
Storage    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Product overview
Description                   Anti-NPPB rabbit polyclonal antibody
Applications        ELISA, IHC 
Immunogen               Synthetic peptide of human NPPB
Reactivity                 Human
Content                     0.5 mg/ml
Host species               Rabbit
Ig class                  Immunogen-specific rabbit IgG
Purification                 Antigen affinity purification

Anti-NPPB antibody
Target information
Symbol                 NPPB
Full name                 natriuretic peptide B
Synonyms    BNP
Swissprot    P16860

Target Background
This gene is a member of the natriuretic peptide family and encodes a secreted protein which functions as a cardiac hormone. The protein undergoes two cleavage events, one within the cell and a second after secretion into the blood. The protein's biological actions include natriuresis, diuresis, vasorelaxation, inhibition of renin and aldosterone secretion, and a key role in cardiovascular homeostasis. A high concentration of this protein in the bloodstream is indicative of heart failure. Mutations in this gene have been associated with postmenopausal osteoporosis.

Anti-NPPB antibody
Applications
Immunohistochemistry
Predicted cell location: Cytoplasm
Positive control: Human cervical cancer
Recommended dilution: 40-150    Predicted cell location: Cytoplasm
Positive control: Human thyroid cancer
Recommended dilution: 40-150