Product overview Description Anti-CD48 rabbit polyclonal antibody Applications ELISA, WB, IHC Immunogen Fusion protein of human CD48 Reactivity Human Content 1.68 mg/ml Host species Rabbit Ig class Immunogen-specific rabbit IgG Purification Antigen affinity purification
Target information Symbol CD48 Full name CD48 molecule Synonyms BCM1; BLAST; hCD48; mCD48; BLAST1; SLAMF2; MEM-102 Swissprot P09326
Target Background This gene encodes a member of the CD2 subfamily of immunoglobulin-like receptors which includes SLAM (signaling lymphocyte activation molecules) proteins. The encoded protein is found on the surface of lymphocytes and other immune cells, dendritic cells and endothelial cells, and participates in activation and differentiation pathways in these cells. The encoded protein does not have a transmembrane domain, however, but is held at the cell surface by a GPI anchor via a C-terminal domain which maybe cleaved to yield a soluble form of the receptor. Multiple transcript variants encoding different isoforms have been found for this gene.