Product overview
Description Anti-CC2D1A rabbit polyclonal antibody
Applications ELISA, IHC
Immunogen Synthetic peptide of human CC2D1A
Reactivity Human, Mouse, Rat
Content 1 mg/ml
Host species Rabbit
Ig class Immunogen-specific rabbit IgG
Purification Antigen affinity purification
Target information
Symbol CC2D1A
Full name coiled-coil and C2 domain containing 1A
Synonyms MRT3; FREUD-1; Freud-1/Aki1
Swissprot Q6P1N0
Target Background
This gene encodes a transcriptional repressor that binds to a conserved 14-bp 5'-repressor element and regulates expression of the 5-hydroxytryptamine (serotonin) receptor 1A gene in neuronal cells. The DNA binding and transcriptional repressor activities of the protein are inhibited by calcium. A mutation in this gene results in nonsyndromic mental retardation-3.
Applications
Immunohistochemistry
Predicted cell location: Cytoplasm or Nucleus
Positive control: Human liver cancer
Recommended dilution: 30-150 Predicted cell location: Cytoplasm or Nucleus
Positive control: Human colorectal cancer
Recommended dilution: 30-150
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using ml263388(CC2D1A Antibody) at dilution 1/35, on the right is treated with synthetic peptide. (Original magnification: ×200) The image on the left is immunohistochemistry of paraffin-embedded Human colorectal cancer tissue using ml263388(CC2D1A Antibody) at dilution 1/35, on the right is treated with synthetic peptide. (Original magnification: ×200)