Product overview Description Anti-CDC23 rabbit polyclonal antibody Applications ELISA, WB, IHC Immunogen Fusion protein of human CDC23 Reactivity Human, Mouse Content 0.2 mg/ml Host species Rabbit Ig class Immunogen-specific rabbit IgG Purification Antigen affinity purification
Target information Symbol CDC23 Full name cell division cycle 23 Synonyms APC8; CUT23; ANAPC8 Swissprot Q9UJX2
Target Background The protein encoded by this gene shares strong similarity with Saccharomyces cerevisiae Cdc23, a protein essential for cell cycle progression through the G2/M transition. This protein is a component of anaphase-promoting complex (APC), which is composed of eight protein subunits and highly conserved in eukaryotic cells. APC catalyzes the formation of cyclin B-ubiquitin conjugate that is responsible for the ubiquitin-mediated proteolysis of B-type cyclins. This protein and 3 other members of the APC complex contain the TPR (tetratricopeptide repeat), a protein domain important for protein-protein interaction.