Product overview
Description Anti-Map2 rabbit polyclonal antibody
Applications ELISA, IHC
Immunogen Synthetic peptide of mouse Map2
Reactivity Human, Mouse, Rat
Content 0.1 mg/ml
Host species Rabbit
Ig class Immunogen-specific rabbit IgG
Purification Antigen affinity purification
Target information
Symbol Map2
Full name microtubule-associated protein 2
Synonyms MAP-2; Mtap2; Mtap-2
Swissprot P20357
Target Background
The exact function of MAP2 is unknown but MAPs may stabilize the microtubules against depolymerization. They also seem to have a stiffening effect on microtubules. It contains 3 Tau/MAP repeats. Phosphorylated at serine residues in K-X-G-S motifs by causing MAP/microtubule affinity-regulating kinase (MARK1 or MARK2), detachment from microtubules, and their disassembly.