Product overview
Description Anti-IRS2 rabbit polyclonal antibody
Applications ELISA, IHC
Immunogen Synthetic peptide of human IRS2
Reactivity Human, Mouse
Content 0.6 mg/ml
Host species Rabbit
Ig class Immunogen-specific rabbit IgG
Purification Antigen affinity purification
Target information
Symbol IRS2
Full name insulin receptor substrate 2
Synonyms IRS-2
Swissprot Q9Y4H2
Target Background
This gene encodes the insulin receptor substrate 2, a cytoplasmic signaling molecule that mediates effects of insulin, insulin-like growth factor 1, and other cytokines by acting as a molecular adaptor between diverse receptor tyrosine kinases and downstream effectors. The product of this gene is phosphorylated by the insulin receptor tyrosine kinase upon receptor stimulation, as well as by an interleukin 4 receptor-associated kinase in response to IL4 treatment.