Anti-GHSR antibody

Anti-GHSR antibody

Cat. No.    JK160429
Package    25 μl/100 μl/200 μl
Storage    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Product overview
Description                   Anti-GHSR rabbit polyclonal antibody
Applications        ELISA, WB 
Immunogen               Synthetic peptide of human GHSR
Reactivity                 Human, Mouse, Rat
Content                     1 mg/ml
Host species               Rabbit
Ig class                  Immunogen-specific rabbit IgG
Purification                 Antigen affinity purification

Target information
Symbol                 GHSR
Full name                 growth hormone secretagogue receptor
Synonyms    
Swissprot    Q92847

Target Background
This gene encodes a member of the G-protein coupled receptor family. The encoded protein may play a role in energy homeostasis and regulation of body weight. Two identified transcript variants are expressed in several tissues and are evolutionary conserved in fish and swine. One transcript, 1a, excises an intron and encodes the functional protein; this protein is the receptor for the Ghrelin ligand and defines a neuroendocrine pathway for growth hormone release. The second transcript (1b) retains the intron and does not function as a receptor for Ghrelin; however, it may function to attenuate activity of isoform 1a. Mutations in this gene are associated with autosomal idiopathic short stature.