GBE1 is a glycogen branching enzyme that catalyzes the transfer of alpha-1, 4-linked glucosyl units from the outer end of a glycogen chain to an alpha-1, 6 position on the same or a neighboring glycogen chain. Branching of the chains is essential to increase the solubility of the glycogen molecule and, consequently, in reducing the osmotic pressure within cells. Highest level of this enzyme are found in liver and muscle. Mutations in this gene are associated with glycogen storage disease IV (also known as Andersen's disease).
Target
GBE1
Reactivity
Human, Mouse
Host
Rabbit
Clonality
Polyclonal
Tested Applications
WB, IF/ICC
Recommended dilutions
Optimal dilutions/concentrations should be determined by the end user.
This GBE1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 527-556 amino acids from the Central region of human GBE1.
Storage
Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles.
Swiss Prot
Q04446
Buffer
PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.