Anti-SIAH2 antibody

Anti-SIAH2 antibody

Cat. No.     JC262198
Package    25 μl/100 μl/200 μl
Storage    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Product overview
Description                   Anti-SIAH2 rabbit polyclonal antibody
Applications        ELISA, IHC 
Immunogen               Synthetic peptide of human SIAH2
Reactivity                 Human, Mouse, Rat
Content                     0.4 mg/ml
Host species               Rabbit
Ig class                  Immunogen-specific rabbit IgG
Purification                 Antigen affinity purification

Target information
Symbol                 SIAH2
Full name                 siah E3 ubiquitin protein ligase 2
Synonyms    hSiah2
Swissprot    O43255

Target Background
This gene encodes a protein that is a member of the seven in absentia homolog (SIAH) family. The protein is an E3 ligase and is involved in ubiquitination and proteasome-mediated degradation of specific proteins. The activity of this ubiquitin ligase has been implicated in regulating cellular response to hypoxia.

Applications
Immunohistochemistry
Predicted cell location: Cytoplasm
Positive control: Human brain
Recommended dilution: 10-50    Predicted cell location: Cytoplasm
Positive control: Human breast cancer
Recommended dilution: 10-50
            
The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using ml262198(SIAH2 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: ×200)    The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using ml262198(SIAH2 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: ×200)

ELISA
Recommended dilution: 1000-2000