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Multidrug resistance protein 1

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  • Signalway Antibody已认证
  • USA
  • AP79415
  • 2025年07月13日
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 保存条件

      Store at -20˚C

    • 英文名

      Multidrug resistance protein 1

    • 库存

      详询

    • 供应商

      南京莱富赛

    • 规格

      详询

    host_species:E.coli

    purification:>90% by SDS-PAGE

    specificity:Human

    other_names:MDR1,PGY1,ATP-binding cassette sub-family B member 1,P-glycoprotein 1,CD243

    accession_no:P08183
    Gene name:ABCB1

    calculated_mw:31.35

    tag info:His

    Immunogen Description:996-1280AA

    formulation:50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole,10%glycerol(PH8.0)

    storage:Store at -20C. (Avoid repeated freezing and thawing.)
    Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.

    background:Energy-dependent efflux pump responsible for decreased drug accumulation in multidrug-resistant cells.

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    图标文献和实验
    相关实验
    • Multidrug Resistance in Cancer

      of overcoming intrinsic multidrug resistance of tumours have been developed but methods for overcoming tumour resistance mediated by host cells are still at an early stage and require further research.

    • Mechanisms of Multidrug Resistance in Cancer

      The development of multidrug resistance (MDR) to chemotherapy remains a major challenge in the treatment of cancer. Resistance exists against every effective anticancer drug and can develop by numerous mechanisms including decreased drug

    • Overcoming Multidrug Resistance by RNA Interference

      The ATP-binding cassette (ABC)-transporter P-glycoprotein (Pgp, also known as ABCB1) is the best characterized factor involved in multidrug resistance (MDR) of cancer cells. Pgp, which is encoded by the MDR1 gene, acts as a membrane-embedded

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