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- Signalway Antibody
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- AP79219
- 2025年07月10日
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- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
Store at -20˚C
- 英文名：
Coagulation factor VII
- 库存：
详询
- 供应商：
南京莱富赛
- 规格：
详询
host_species:E.coli
purification:>90% by SDS-PAGE
specificity:Mouse
other_names:Cf7,Serum prothrombin conversion accelerator
accession_no:P70375
Gene name:F7
calculated_mw:16.72
tag info:His
Immunogen Description:42-193AA
formulation:50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole,10%glycerol(PH8.0)
storage:Store at -20C. (Avoid repeated freezing and thawing.)
Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.
background:Initiates the extrinsic pathway of blood coagulation. Serine protease that circulates in the blood in a zymogen form. Factor VII is converted to factor VIIa by factor Xa, factor XIIa, factor IXa, or thrombin by minor proteolysis. In the presence of tissue factor and calcium ions, factor VIIa then converts factor X to factor Xa by limited proteolysis. Factor VIIa will also convert factor IX to factor IXa in the presence of tissue factor and calcium.
产品详细信息请点击：Coagulation factor VII
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文献和实验Identification of Mutations in the Human Factor VII Gene
It has been recognized from the early 1800s that activation of coagulation can be initiated by the exposure of subendothelial layers (tissue factor), but it was the 1940s before factor VII (FVII) was included in this event
Use of Human Hepatocytes to Investigate Blood Coagulation Factor
Coagulation is the complex process by which activation of plasmatic haemostasis proteins ends up with the generation of fibrin. Most of the plasma coagulation proteins are synthesized in hepatocytes. The aim of this chapter
血液凝固因子 blood coagulation factor
血液凝固因子 blood coagulation factor 指直接参与血液凝固机制的各种因子，亦称血凝因子或血浆凝固因子。自 P． Morawitz（ 1903）研究凝血活素以后，由于研究的进步，各种因子相继发现，为避免命名混乱，成立了国际血凝因子名称审定委员会。该委员会提议对一般已承认的血凝因子附以罗马数字来统一命名。继 1954年后，在 1959年第四次委员会上制定了如下页表所示名称。这里第Ⅺ因子和第Ⅻ因子，亦称接触因子（ con－ tact factor）。
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