- 询价
- Signalway Antibody
- USA
- AP79174
- 2025年07月11日
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- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
Store at -20˚C
- 英文名：
Ubiquitin carboxyl-terminal hydrolase isozyme L1
- 库存：
详询
- 供应商：
南京莱富赛
- 规格：
详询
host_species:E.coli
purification:>90% by SDS-PAGE
specificity:Pig
other_names:Ubiquitin thioesterase L1
accession_no:Q6SEG5
Gene name:UCHL1
calculated_mw:24.2
tag info:His
Immunogen Description:1-220AA
formulation:50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole,10%glycerol(PH8.0)
storage:Store at -20C. (Avoid repeated freezing and thawing.)
Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.
background:Ubiquitin-protein hydrolase involved both in the processing of ubiquitin precursors and of ubiquitinated proteins. This enzyme is a thiol protease that recognizes and hydrolyzes a peptide bond at the C-terminal glycine of ubiquitin. Also binds to free monoubiquitin and may prevent its degradation in lysosomes. The homodimer may have ATP-independent ubiquitin ligase activity.
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文献和实验（Ubiquitin C-terminal hydrolase-L1，UCH-L1）是一种主要分布于脑内，同时对人类大脑具有高度特异性的球蛋白。 癫痫大发作组脑脊液 UCH-L1 水平显著高于部分性发作组和对照组。癫痫患者的脑脊液 UCHL1 水平与癫痫发作的严重程度和癫痫发作的持续时间密切相关。癫痫发作后 6h 内检验患者血清 UCH-L1 及 S100β 水平，结果显示癫痫组 UCHL-1 及 S100β 水平显著高于精神源性非癫痫性发作组及健康人群组，精神源性非癫痫性发作组 S100β 水平显著高于健康对照
spermatogonia coexpress GPR125, integrin, alpha 6 (ITGA6), THY1 (also known as CD90), GFRA1, and ubiquitin carboxyl-terminal esterase L1 (UCHL1), markers for rodent or pig SSCs/progenitors, suggesting that GPR125- and GFRA1-positive spermatogonia
A Method for Assaying Deubiquitinating Enzymes
). The purified Ub-specific protease-6 (yUBP-6) in yeast and cUBP41, Ub C-terminal hydrolase-1 (cUCH-1), cUCH-6, and cUCH-8 in chick skeletal muscle were prepared as described (13 , 15 -18 ). Ub-PESTc was purified from an E. coli strain AR13 carrying pNMHUB-PESTc
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