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- 详细信息
- 文献和实验
- 技术资料
- 保存条件:
Store at -20˚C
- 英文名:
ATP-binding cassette sub-family A member 7
- 库存:
详询
- 供应商:
南京莱富赛
- 规格:
详询
host_species:E.coli
purification:>90% by SDS-PAGE
specificity:Mouse
other_names:null
accession_no:Q91V24
Gene name:Abca7
calculated_mw:
tag info:His
Immunogen Description:Recombinant Protein
formulation:50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole,10%glycerol(PH8.0)
storage:Store at -20C. (Avoid repeated freezing and thawing.)
Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.
background:Plays a role in phagocytosis by macrophages of apoptotic cells. Binds APOA1 and may function in apolipoprotein-mediated phospholipid efflux from cells. May also mediate cholesterol efflux. May regulate cellular ceramide homeostasis during keratinocytes differentiation.
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文献和实验Pharmacogenetics of ATP-Binding Cassette Transporters and Clinical Implications
Drug resistance is a severe limitation of chemotherapy of various malignancies. In particular efflux transporters of the ATP-binding cassette family such as ABCB1 (P-glycoprotein), the ABCC (multidrug resistance-associated protein) family
The 14-3-3 intracellular phosphoserine/threonine-binding proteins are adapter molecules that regulate signal transduction, cell cycle, nutrient sensing, apoptotic, and cytoskeletal pathways. There are seven 14-3-3 family members, encoded
Quantitative Analysis of ATP-Dependent Gating of CFTR
CFTR, the chloride ion channel encoded by the gene mutated in cystic fibrosis patients, has been the subject of intense investigation since its discovery in 1989 (1 ). A member of the ATP Binding Cassette (ABC) superfamily, the CFTR channel
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