- 询价
- Signalway Antibody
- USA
- AP78838
- 2025年07月12日
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- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
Store at -20˚C
- 英文名：
Peroxisome proliferator-activated receptor gamma coactivator 1-alpha
- 库存：
详询
- 供应商：
南京莱富赛
- 规格：
详询
host_species:E.coli
purification:>90% by SDS-PAGE
specificity:Bovine
other_names:PGC1,PGC1A,PPARGC1
accession_no:Q865B7
Gene name:PPARGC1A
calculated_mw:
tag info:His
Immunogen Description:C-terminal
formulation:50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole,10%glycerol(PH8.0)
storage:Store at -20C. (Avoid repeated freezing and thawing.)
Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.
background:Transcriptional coactivator for steroid receptors and nuclear receptors. Greatly increases the transcriptional activity of PPARG and thyroid hormone receptor on the uncoupling protein promoter. Can regulate key mitochondrial genes that contribute to the program of adaptive thermogenesis. Plays an essential role in metabolic reprogramming in response to dietary availability through coordination of the expression of a wide array of genes involved in glucose and fatty acid metabolism. Induces the expression of PERM1 in the skeletal muscle in an ESRRA-dependent manner. Also involved in the integration of the circadian rhythms and energy metabolism. Required for oscillatory expression of clock genes, such as ARNTL/BMAL1 and NR1D1, through the coactivation of RORA and RORC, and metabolic genes, such as PDK4 and PEPCK.
产品详细信息请点击：Peroxisome proliferator-activated receptor gamma coactivator 1-alpha
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文献和实验Peroxisome proliferator-activated receptor gamma coactivator 1 alpha (PGC-1α) is a nuclear transcriptional coactivator that regulates the genes involved in energy metabolism. Recent evidence has been provided that alternative splicing
Capture and Qualitative Analysis of the Activated Fc Receptor Complex from Live Cells
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Isolation of a p300/CBP Cointegrator-Associated Protein Coactivator Complex
Nuclear hormone receptors belong to a large family of structurally related proteins that include the steroid, retinoic acid, and vitamin D receptors. These receptors function as ligand-activated transcription factors and regulate complex
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