- 询价
- Signalway Antibody
- USA
- AP78671
- 2025年07月12日
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- 详细信息
- 询价记录
- 文献和实验
- 技术资料
- 保存条件：
Store at -20˚C
- 英文名：
Transferrin receptor protein 1
- 库存：
详询
- 供应商：
南京莱富赛
- 规格：
详询
host_species:E.coli
purification:>90% by SDS-PAGE
specificity:Pig
other_names:CD71
accession_no:Q8HZV3
Gene name:TFRC
calculated_mw:
tag info:His
Immunogen Description:Recombinant protein
formulation:50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole,10%glycerol(PH8.0)
storage:Store at -20C. (Avoid repeated freezing and thawing.)
Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.
background:Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system (By similarity). Positively regulates T and B cell proliferation through iron uptake.
产品详细信息请点击：Transferrin receptor protein 1
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文献和实验Methods for Manipulation of Transferrin-Binding Proteins
To obtain iron, a necessary nutrient, meningococci and several other human and veterinary pathogens have iron-acquisition systems, which are expressed in vivo during infection. One target of iron-acquisition systems is transferrin (Tf
G Protein-Coupled Receptor Pharmacogenetics
Common G protein-coupled receptor (GPCR) gene variants that encode receptor proteins with a distinct sequence may alter drug efficacy without always resulting in a disease phenotype. GPCR genetic loci harbor numerous variants, such as DNA
Receptor Isolation and Characterization: From Protein to Gene
capture the biomolecule of interest. Isolation of a protein by affinity chromatography is a very effective technique. It provides the protein in a pure state, enabling its identification by partial sequencing, either by mass spectrometry or by N-terminal
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