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- Signalway Antibody
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- 2025年07月13日
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- 详细信息
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- 技术资料
- 保存条件：
Store at -20˚C
- 英文名：
Coagulation factor XII
- 库存：
详询
- 供应商：
南京莱富赛
- 规格：
详询
host_species:E.coli
purification:>90% by SDS-PAGE
specificity:Human
other_names:Hageman factor,HAF
accession_no:P00748
Gene name:F12
calculated_mw:26.73
tag info:His
Immunogen Description:373-615AA
formulation:50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole,10%glycerol(PH8.0)
storage:Store at -20C. (Avoid repeated freezing and thawing.)
Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.
background:Factor XII is a serum glycoprotein that participates in the initiation of blood coagulation, fibrinolysis, and the generation of bradykinin and angiotensin. Prekallikrein is cleaved by factor XII to form kallikrein, which then cleaves factor XII first to alpha-factor XIIa and then trypsin cleaves it to beta-factor XIIa. Alpha-factor XIIa activates factor XI to factor XIa.
产品详细信息请点击：Coagulation factor XII
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文献和实验Use of Human Hepatocytes to Investigate Blood Coagulation Factor
Coagulation is the complex process by which activation of plasmatic haemostasis proteins ends up with the generation of fibrin. Most of the plasma coagulation proteins are synthesized in hepatocytes. The aim of this chapter
血液凝固因子 blood coagulation factor
血液凝固因子 blood coagulation factor 指直接参与血液凝固机制的各种因子，亦称血凝因子或血浆凝固因子。自 P． Morawitz（ 1903）研究凝血活素以后，由于研究的进步，各种因子相继发现，为避免命名混乱，成立了国际血凝因子名称审定委员会。该委员会提议对一般已承认的血凝因子附以罗马数字来统一命名。继 1954年后，在 1959年第四次委员会上制定了如下页表所示名称。这里第Ⅺ因子和第Ⅻ因子，亦称接触因子（ con－ tact factor）。
Disseminated intravascular coagulation (DIC) is a complex acquired, coagulopathy resulting from excessive thrombin formation. Abnormal tissue factor (TF) expression is a major mechanism initiating DIC in many disorders, including obstetric
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