- 询价
- Signalway Antibody
- USA
- AP78579
- 2025年07月09日
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- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
Store at -20˚C
- 英文名：
Pyruvate kinase PKM
- 库存：
详询
- 供应商：
南京莱富赛
- 规格：
详询
host_species:E.coli
purification:>90% by SDS-PAGE
specificity:Human
other_names:OIP3,PK2,PK3,PKM2,Cytosolic thyroid hormone-binding protein,Opa-interacting protein 3,Pyruvate kinase 2/3,Pyruvate kinase muscle isozyme,Thyroid hormone-binding protein 1,Tumor M2-PK,p58,CTHBP,OIP-3,THBP1
accession_no:P14618
Gene name:PKM
calculated_mw:26.4
tag info:His
Immunogen Description:2-241AA
formulation:50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole,10%glycerol(PH8.0)
storage:Store at -20C. (Avoid repeated freezing and thawing.)
Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.
background:Glycolytic enzyme that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate (PEP) to ADP, generating ATP. Stimulates POU5F1-mediated transcriptional activation. Plays a general role in caspase independent cell death of tumor cells. The ratio between the highly active tetrameric form and nearly inactive dimeric form determines whether glucose carbons are channeled to biosynthetic processes or used for glycolytic ATP production. The transition between the 2 forms contributes to the control of glycolysis and is important for tumor cell proliferation and survival.
产品详细信息请点击：Pyruvate kinase PKM
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文献和实验缩写式为 ATP：丙酮酸 -2-O-磷酸转移酶。在糖酵解系统里，它是催化形成第二个 ATP反应的酶。 EC2． 7． 1． 40。能以磷酸烯醇（ phosphoenolpyruv- ate）丙酮酸和 ADP生成丙酮酸和 ATP·Δ Go1 ＝ -7． 5kcal。除需要二价金属离子外（ Mg2 ＋ 和 Mn2 ＋ ）外，还需要一价金属离子（ K＋ ． Rb＋ ， Cs＋ ），在生理上起作用的大概是 K＋ 。分子量约 25万。
Serum Creatine Kinase in Progressive Muscular Dystrophies
Several enzymes originating in muscle show increased activity in the serum of patients affected with different forms of muscular dystrophy (MD). These enzymes include creatine kinase (CK), aldolase, transaminase, and pyruvate kinase (PK
Steady State ATPase Assays Coupled Enzyme System
, in Tris-HCl. Avoid using phosphate buffers for ATPase assays. 2. The coupled enzyme ATPase assay is based on the conversion of phosphoenolpyruvate (PEP) to pyruvate by pyruvate kinase (PK) coupled to the conversion
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