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Recombinant Mouse Transcriptio

n factor GATA-4(GATA4)
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  • 询价
  • Signalway Antibody已认证
  • USA
  • AP77773
  • 2025年07月12日
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 保存条件

      Store at -20˚C

    • 英文名

      Recombinant Mouse Transcription factor GATA-4(GATA4)

    • 库存

      详询

    • 供应商

      南京莱富赛

    • 规格

      详询

    host_species:E.coli

    purification:Greater than 85% as determined by SDS-PAGE.

    other_names:GATA-binding factor 4 Gata-4

    accession_no:Q08369

    calculated_mw:49.6 kDa

    tag info:N-terminal 10xHis-tagged and C-terminal Myc-tagged

    Immunogen Description:Expression Region:1-441aa
    Sequence Info:Full Length

    formulation:Tris-based buffer50% glycerol

    storage:The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20℃,-80℃. The shelf life of lyophilized form is 12 months at -20℃,-80℃.
    Notes:Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.

    background:Transcriptional activator that binds to the consensus sequence 5'-AGATAG-3' and plays a key role in cardiac development. In cooperation with TBX5, it binds to cardiac super-enhancers and promotes cardiomyocyte gene expression, while it downregulates endocardial and endothelial gene expression. Involved in bone morphogenetic protein (BMP)-mediated induction of cardiac-specific gene expression. Binds to BMP response element (BMPRE) DNA sequences within cardiac activating regions. Acts as a transcriptional activator of ANF in cooperation with NKX2-5. Promotes cardiac myocyte enlargement. Required during testicular development. May play a role in sphingolipid signaling by regulating the expression of sphingosine-1-phosphate degrading enzyme, spingosine-1-phosphate lyase

    产品详细信息请点击:Recombinant Mouse Transcription factor GATA-4(GATA4)

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