- 询价
- Signalway Antibody
- USA
- AP77177
- 2025年07月14日
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- 详细信息
- 技术资料
- 保存条件：
Store at -20˚C
- 英文名：
Recombinant Human Kelch-like ECH-associated protein 1(KEAP1)
- 库存：
详询
- 供应商：
南京莱富赛
- 规格：
详询
host_species:Yeast
purification:Greater than 90% as determined by SDS-PAGE.
other_names:Cytosolic inhibitor of Nrf2
accession_no:Q14145
calculated_mw:71.7 kDa
tag info:N-terminal 6xHis-tagged
Immunogen Description:Expression Region:1-624aa
Sequence Info:Full Length
formulation:Tris-based buffer50% glycerol
storage:The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20℃,-80℃. The shelf life of lyophilized form is 12 months at -20℃,-80℃.
Notes:Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.
background:Acts as a substrate adapter protein for the E3 ubiquitin ligase complex formed by CUL3 and RBX1 and targets NFE2L2,NRF2 for ubiquitination and degradation by the proteasome, thus resulting in the suppression of its transcriptional activity and the repression of antioxidant response element-mediated detoxifying enzyme gene expression. Retains NFE2L2,NRF2 and may also retain BPTF in the cytosol. Targets PGAM5 for ubiquitination and degradation by the proteasome.
产品详细信息请点击：Recombinant Human Kelch-like ECH-associated protein 1(KEAP1)
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