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- Signalway Antibody
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- AP77027
- 2025年07月16日
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- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
Store at -20˚C
- 英文名：
Recombinant Human GrpE protein homolog 1, mitochondrial(GRPEL1)
- 库存：
详询
- 供应商：
南京莱富赛
- 规格：
详询
host_species:E.coli
purification:Greater than 90% as determined by SDS-PAGE.
other_names:HMGE Mt-GrpE#1
accession_no:Q9HAV7
calculated_mw:48.3 kDa
tag info:N-terminal GST-tagged
Immunogen Description:Expression Region:1-217aa
Sequence Info:Full Length
formulation:Tris-based buffer50% glycerol
storage:The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20℃,-80℃. The shelf life of lyophilized form is 12 months at -20℃,-80℃.
Notes:Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.
background:Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. Seems to control the nucleotide-dependent binding of mitochondrial HSP70 to substrate proteins.
产品详细信息请点击：Recombinant Human GrpE protein homolog 1, mitochondrial(GRPEL1)
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文献和实验Preparation of Human Mitochondrial Single-Stranded DNA-Binding Protein
to avoid the time and expense of human tissue culture. This chapter focuses on the subcloning, purification, and initial functional validation of the recombinant human mitochondrial single-stranded DNA-binding protein. The cDNA encoding the mature form
in initiation and elongation of DNA strands in mitochondrial DNA (mtDNA) replication, that has been documented genetically by the fact that a null mutation in the gene for the yeast homolog (RIM1) results in complete loss of mtDNA in vivo (4 ). More recently
involving nuclear-encoded proteins that are required at the mitochondrial DNA replication fork, which often leads to human disorders and to animal lethality during development. DNA polymerase γ (pol γ), the mitochondrial replicase, and the mitochondrial
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