Recombinant Influenza A virus

host_species:E.coli

purification:Greater than 90% as determined by SDS-PAGE.

other_names:

accession_no:R4NN21

calculated_mw:72.2 kDa

tag info:N-terminal 6xHis-SUMO-tagged

Immunogen Description:Expression Region:19-524aa
Sequence Info:Partial

formulation:Tris-based buffer50% glycerol

storage:The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20℃,-80℃. The shelf life of lyophilized form is 12 months at -20℃,-80℃.
Notes:Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.

background:Binds to sialic acid-containing receptors on the cell surface, bringing about the attachment of the virus particle to the cell. This attachment induces virion internalization of about two third of the virus particles through clathrin-dependent endocytosis and about one third through a clathrin- and caveolin-independent pathway. Plays a major role in the determination of host range restriction and virulence. Class I viral fusion protein. Responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the mbrane of the endocytosed virus particle with the endosomal mbrane. Low pH in endosomes induces an irreversible conformational change in HA2, releasing the fusion hydrophobic peptide. Several trimers are required to form a competent fusion pore.

产品详细信息请点击：Recombinant Influenza A virus Hemagglutinin(HA),partial