Anti-RBM38 antibody

Anti-RBM38 antibody

Cat. No.     JC262114
Package    25 μl/100 μl/200 μl
Storage    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Product overview
Description                   Anti-RBM38 rabbit polyclonal antibody
Applications        ELISA, IHC 
Immunogen               Synthetic peptide of human RBM38
Reactivity                 Human, Mouse
Content                     1.7 mg/ml
Host species               Rabbit
Ig class                  Immunogen-specific rabbit IgG
Purification                 Antigen affinity purification

Target information
Symbol                 RBM38
Full name                 RNA binding motif protein 38
Synonyms    RNPC1; SEB4B; SEB4D; HSRNASEB; dJ800J21.2
Swissprot    Q9H0Z9

Target Background
RBM38 is a cell cycle protein found in the cytosol and the nucleus that exists as two alternatively spliced isoforms, 1 (RNPC1a) and 2 (RNPC1b), of 239 and 121 amino acids, respectively. Independent of p53 expression, RBM38 isoform 1 induces cell cycle arrest in G1 phase through maintaining transcript stability at the 3’-UTR of p21, a regulator of cell cycle progression at S phase. RBM38 is also an mRNA splicing factor that regulates the expression of FGFR2. RBM38 contains one RRM (RNA recognition motif) domain.

Applications
Immunohistochemistry
Predicted cell location: Cytoplasm
Positive control: Human esophagus cancer
Recommended dilution: 50-300    Predicted cell location: Cytoplasm
Positive control: Human liver cancer
Recommended dilution: 50-300
            
The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using ml262114(RBM38 Antibody) at dilution 1/45, on the right is treated with synthetic peptide. (Original magnification: ×200)    The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using ml262114(RBM38 Antibody) at dilution 1/45, on the right is treated with synthetic peptide. (Original magnification: ×200)

ELISA
Recommended dilution: 2000-10000