Anti-RHEBL1 antibody

Anti-RHEBL1 antibody

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  • 询价
  • gelatins
  • JC123857
  • 进口/国产
  • 2025年07月13日
  • ELISA, WB
  • Rabbit
  • 人/动物/植物
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    • 详细信息
    • 技术资料
    • 供应商

      上海机纯实业有限公司

    • 库存

      大量

    • 克隆性

      多克隆

    • 保质期

      12个月

    • 抗体英文名

      Anti-RHEBL1 antibody

    • 宿主

      Rabbit

    • 适应物种

      人/动物/植物

    • 应用范围

      ELISA, WB

    • 浓度

      Human, Mouse, Rat 0.6 mg/ml

    • 保存条件

      -20°C

    • 规格

      25 μl/100 μl/200 μl

    Anti-RHEBL1 antibody

    Cat. No.     JC123857        
    Package    25 μl/100 μl/200 μl
    Storage    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

    Product overview
    Description                   Anti-RHEBL1 rabbit polyclonal antibody
    Applications        ELISA, IHC 
    Immunogen               Fusion protein of human RHEBL1
    Reactivity                 Human, Mouse, Rat
    Content                     0.6 mg/ml
    Host species               Rabbit
    Ig class                  Immunogen-specific rabbit IgG
    Purification                 Antigen affinity purification

    Anti-RHEBL1 antibody
    Target information
    Symbol                 RHEBL1
    Full name                 Ras homolog enriched in brain like 1
    Synonyms    RHEBL1c
    Swissprot    Q8TAI7

    Target Background
    RhebL1 (ras homolog enriched in brain-like protein 1), also known as Rheb2 or GTPase RhebL1, is a 183 amino acid protein that belongs to the small GTPase superfamily and Rheb family. Localizing to the cell membrane as well as the cytoplasm, RhebL1 is ubiquitously expressed and is increased two-fold in many tumor cell lines. RhebL1 exhibits GTPase activity and may activate NF-kappa-B-mediated gene transcription. Regulating the activity of Rictor, RhebL1 also promotes signal transduction. RhebL1 exists as two alternatively spliced isoforms and is encoded by a gene that maps to human chromosome 12q13.12 and mouse chromosome 15 F1. Human chromosome 12 encodes over 1,100 genes and comprises approximately 4.5% of the human genome. Chromosome 12 is associated with a variety of diseases and afflictions, including hypochondrogenesis, achondrogenesis, Kniest dysplasia, Noonan syndrome and trisomy 12p, which causes facial developmental defects and seizure disorders. Binds GTP and exhibits intrinsic GTPase activity. May activate NF-kappa-B-mediated gene transcription. Promotes signal transduction through MTOR, activates RPS6KB1, and is a downstream target of the small GTPase-activating proteins TSC1 and TSC2.

    Anti-RHEBL1 antibody
    Applications
    Immunohistochemistry
    Predicted cell location: Cytoplasm or Nucleus
    Positive control: Human lung cancer
    Recommended dilution: 25-100    Predicted cell location: Cytoplasm or Nucleus
    Positive control: Human prostate cancer
    Recommended dilution: 25-100

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