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- 详细信息
- 文献和实验
- 技术资料
- 供应商:
江西江蓝纯生物试剂有限公司
- 库存:
大量
- 克隆性:
多克隆
- 保质期:
1年
- 抗体英文名:
Anti-ATP2A1 antibody
- 宿主:
Rabbit
- 浓度:
0.7 mg/ml
- 保存条件:
-20°C
- 规格:
25 μl/100 μl/200 μl
Cat. No. JC261908
Package 25 μl/100 μl/200 μl
Storage -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Product overview
Description Anti-ATP2A1 rabbit polyclonal antibody
Applications ELISA, IHC
Immunogen Synthetic peptide of human ATP2A1
Reactivity Human
Content 0.7 mg/ml
Host species Rabbit
Ig class Immunogen-specific rabbit IgG
Purification Antigen affinity purification
Target information
Symbol ATP2A1
Full name ATPase, Ca++ transporting, cardiac muscle, fast twitch 1
Synonyms ATP2A; SERCA1
Swissprot O14983
Target Background
This gene encodes one of the SERCA Ca(2+)-ATPases, which are intracellular pumps located in the sarcoplasmic or endoplasmic reticula of muscle cells. This enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen, and is involved in muscular excitation and contraction. Mutations in this gene cause some autosomal recessive forms of Brody disease, characterized by increasing impairment of muscular relaxation during exercise. Alternative splicing results in three transcript variants encoding different isoforms.
Applications
Immunohistochemistry
Predicted cell location: Cytoplasm
Positive control: Human liver cancer
Recommended dilution: 50-200 Predicted cell location: Cytoplasm
Positive control: Human brain
Recommended dilution: 50-200
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using ml261908(ATP2A1 Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: ×200) The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using ml261908(ATP2A1 Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: ×200)
ELISA
Recommended dilution: 2000-5000
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