- 询价
- 晶抗生物
- JK125080
- 上海
- 2025年07月16日
- 科研试验
- Rabbit
- Human,Mouse,Rat,Chicken,Dog,Cow,Rabbit,Sheep
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- 详细信息
- 技术资料
- 供应商：
上海晶抗生物工程有限公司
- 库存：
大量
- 克隆性：
多克隆
- 保质期：
1年
- 抗体英文名：
Anti-SHC1 antibody
- 宿主：
Rabbit
- 适应物种：
Human,Mouse,Rat,Chicken,Dog,Cow,Rabbit,Sheep
- 应用范围：
科研试验
- 保存条件：
-20°C
- 规格：
25 μl/100 μl/200 μl
Anti-SHC1 antibody
Cat. No. JK125080
Package 25 μl/100 μl/200 μl
Storage -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Product overview
Description Anti-SHC1 rabbit polyclonal antibody
Applications ELISA, WB, IHC
Immunogen Fusion protein of human SHC1
Reactivity Human, Mouse, Rat
Content 0.72 mg/ml
Host species Rabbit
Ig class Immunogen-specific rabbit IgG
Purification Antigen affinity purification
Target information
Symbol SHC1
Full name SHC adaptor protein 1
Synonyms SHC; SHCA
Swissprot P29353
Target Background
This gene encodes three main isoforms that differ in activities and subcellular location. While all three are adapter proteins in signal transduction pathways, the longest (p66Shc) may be involved in regulating life span and the effects of reactive oxygen species. The other two isoforms, p52Shc and p46Shc, link activated receptor tyrosine kinases to the Ras pathway by recruitment of the GRB2/SOS complex. p66Shc is not involved in Ras activation. Unlike the other two isoforms, p46Shc is targeted to the mitochondrial matrix. Several transcript variants encoding different isoforms have been found for this gene.
Cat. No. JK125080
Package 25 μl/100 μl/200 μl
Storage -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Product overview
Description Anti-SHC1 rabbit polyclonal antibody
Applications ELISA, WB, IHC
Immunogen Fusion protein of human SHC1
Reactivity Human, Mouse, Rat
Content 0.72 mg/ml
Host species Rabbit
Ig class Immunogen-specific rabbit IgG
Purification Antigen affinity purification
Target information
Symbol SHC1
Full name SHC adaptor protein 1
Synonyms SHC; SHCA
Swissprot P29353
Target Background
This gene encodes three main isoforms that differ in activities and subcellular location. While all three are adapter proteins in signal transduction pathways, the longest (p66Shc) may be involved in regulating life span and the effects of reactive oxygen species. The other two isoforms, p52Shc and p46Shc, link activated receptor tyrosine kinases to the Ras pathway by recruitment of the GRB2/SOS complex. p66Shc is not involved in Ras activation. Unlike the other two isoforms, p46Shc is targeted to the mitochondrial matrix. Several transcript variants encoding different isoforms have been found for this gene.
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Anti-SHC1 antibody
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