Product overview Description Anti-MCC rabbit polyclonal antibody
Applications ELISA, IHC
Immunogen Synthetic peptide of human MCC
Reactivity Human
Content 0.7 mg/ml
Host species Rabbit
Ig class Immunogen-specific rabbit IgG
Purification Antigen affinity purification
Target information Symbol MCC
Full name mutated in colorectal cancers
Synonyms MCC1
Swissprot P23508
Target Background This gene is a candidate colorectal tumor suppressor gene that is thought to negatively regulate cell cycle progression. The orthologous gene in the mouse expresses a phosphoprotein associated with the plasma membrane and membrane organelles, and overexpression of the mouse protein inhibits entry into S phase. Multiple transcript variants encoding different isoforms have been found for this gene.