- 询价
- gelatins
- JC261851
- 上海
- 2025年07月16日
- Rabbit
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- 详细信息
- 文献和实验
- 技术资料
- 供应商：
江西江蓝纯生物试剂有限公司
- 库存：
大量
- 克隆性：
多克隆
- 保质期：
1年
- 抗体英文名：
Anti-CERS6 antibody
- 宿主：
Rabbit
- 浓度：
0.7 mg/ml
- 保存条件：
-20°C
- 规格：
25 μl/100 μl/200 μl
Cat. No. JC261851
Package 25 μl/100 μl/200 μl
Storage -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Product overview
Description Anti-CERS6 rabbit polyclonal antibody
Applications ELISA, IHC
Immunogen Synthetic peptide of human CERS6
Reactivity Human, Mouse
Content 0.7 mg/ml
Host species Rabbit
Ig class Immunogen-specific rabbit IgG
Purification Antigen affinity purification
Target information
Symbol CERS6
Full name ceramide synthase 6
Synonyms CERS5; LASS6
Swissprot Q6ZMG9
Target Background
The LASS (longevity assurance homolog) family members are highly conserved from yeasts to mammals. Six members of this family of proteins have been characterized (LASS1, LASS2, LASS3, LASS4, LASS5 and LASS6) and they all are involved in sphingolipid synthesis. LASS6 is a widely expressed 384 amino acid endoplasmic reticulum, multi-pass membrane protein. On the luminal side of the endoplasmic reticulum membrane, the N-terminal asparagine residue is glycosylated. In cells deficient for CLN9, LASS6 corrects growth and apoptosis, and increases the levels of short ceramide species, such as C14:0- and C16:0-ceramides.
Applications
Immunohistochemistry
Predicted cell location: Nucleus
Positive control: Human ovarian cancer
Recommended dilution: 50-200 Predicted cell location: Nucleus
Positive control: Human brain
Recommended dilution: 50-200
The image on the left is immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using ml261851(CERS6 Antibody) at dilution 1/35, on the right is treated with synthetic peptide. (Original magnification: ×200) The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using ml261851(CERS6 Antibody) at dilution 1/35, on the right is treated with synthetic peptide. (Original magnification: ×200)
ELISA
Recommended dilution: 2000-5000
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