Anti-SCAP antibody

Anti-SCAP antibody

Cat. No.     JC123094        
Package    25 μl/100 μl/200 μl
Storage    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Product overview
Description                   Anti-SCAP rabbit polyclonal antibody
Applications        ELISA, IHC 
Immunogen               Fusion protein of human SCAP
Reactivity                 Human, Mouse, Rat
Content                     0.2 mg/ml
Host species               Rabbit
Ig class                  Immunogen-specific rabbit IgG
Purification                 Antigen affinity purification

Anti-SCAP antibody
Target information
Symbol                 SCAP
Full name                 SREBF chaperone
Synonyms    
Swissprot    Q12770

Target Background
This gene encodes a protein with a sterol sensing domain (SSD) and seven WD domains. In the presence of cholesterol, this protein binds to sterol regulatory element binding proteins (SREBPs) and mediates their transport from the ER to the Golgi. The SREBPs are then proteolytically cleaved and regulate sterol biosynthesis.

Anti-SCAP antibody
Applications
Immunohistochemistry
Predicted cell location: Cytoplasm
Positive control: Human breast cancer
Recommended dilution: 25-100    Predicted cell location: Cytoplasm
Positive control: Human esophagus cancer
Recommended dilution: 25-100