Anti-GTF2I antibody

Anti-GTF2I antibody

Cat. No.     JC261479
Package    25 μl/100 μl/200 μl
Storage    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Product overview
Description                   Anti-GTF2I rabbit polyclonal antibody
Applications        ELISA, WB, IHC 
Immunogen               Synthetic peptide of human GTF2I
Reactivity                 Human, Mouse, Rat
Content                     0.4 mg/ml
Host species               Rabbit
Ig class                  Immunogen-specific rabbit IgG
Purification                 Antigen affinity purification

Target information
Symbol                 GTF2I
Full name                 general transcription factor IIi
Synonyms    WBS; DIWS; SPIN; IB291; BAP135; BTKAP1; TFII-I; WBSCR6; GTFII-I
Swissprot    P78347

Target Background
This gene encodes a phosphoprotein containing six characteristic repeat motifs. The encoded protein binds to the initiator element (Inr) and E-box element in promoters and functions as a regulator of transcription. This locus, along with several other neighboring genes, is deleted in Williams-Beuren syndrome. There are many closely related genes and pseudogenes for this gene on chromosome 7. This gene also has pseudogenes on chromosomes 9, 13, and 21. Alternatively spliced transcript variants encoding multiple isoforms have been observed.

Applications
Immunohistochemistry
Predicted cell location: Nucleus
Positive control: Human thyroid cancer
Recommended dilution: 50-200    Predicted cell location: Nucleus
Positive control: Human cervical cancer
Recommended dilution: 50-200
            
The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using ml261479(GTF2I Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: ×200)    The image on the left is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using ml261479(GTF2I Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: ×200)
Western blotting
Predicted band size:112 kDa
Positive control:HepG2 cells 
Recommended dilution: 200-1000