Product overview
Description Anti-PDP1 rabbit polyclonal antibody
Applications ELISA, WB, IHC
Immunogen Fusion protein of human PDP1
Reactivity Human, Mouse, Rat
Content 0.2 mg/ml
Host species Rabbit
Ig class Immunogen-specific rabbit IgG
Purification Antigen affinity purification
Target information
Symbol PDP1
Full name pyruvate dehyrogenase phosphatase catalytic subunit 1
Synonyms PDH; PDP; PDPC; PPM2C
Swissprot Q9P0J1
Target Background
Pyruvate dehydrogenase (E1) is one of the three components (E1, E2, and E3) of the large pyruvate dehydrogenase complex. Pyruvate dehydrogenase kinases catalyze phosphorylation of serine residues of E1 to inactivate the E1 component and inhibit the complex. Pyruvate dehydrogenase phosphatases catalyze the dephosphorylation and activation of the E1 component to reverse the effects of pyruvate dehydrogenase kinases. Pyruvate dehydrogenase phosphatase is a heterodimer consisting of catalytic and regulatory subunits.