品牌:miltenyi,产品名称:CD197 (CCR7)-Biotin, mouse 60 tests CD197 (CCR7) antibodies, mouse - Miltenyi Biotec 货号:130-110-367 Clone REA685 recognizes the mouse CD197 (CCR7) antigen, a chemokine receptor for chemokines CCL19 and CCL21. CD197, like other chemokine receptors has seven transmembrane spanning domains and signals via G proteins. Expression of CD197 is found on semi-mature and mature dendritic cells (DCs), naive B and T cells, regulatory T (Treg) cells, a subpopulation of T cells called central memory T cells, and non-immune malignant cells. CD197 is involved in regulating homing of immune cells, immunity to pathogens, immune tolerance, development and function of Tregs, and manifestation of autoimmunity. Additional information: Clone REA685 displays negligible binding to Fc receptors.