Product overview
Description Anti-CXCR4 rabbit polyclonal antibody
Applications ELISA, IHC
Immunogen Synthetic peptide of human CXCR4
Reactivity Human, Mouse, Rat
Content 0.6 mg/ml
Host species Rabbit
Ig class Immunogen-specific rabbit IgG
Purification Antigen affinity purification
Target information
Symbol CXCR4
Full name chemokine (C-X-C motif) receptor 4
Synonyms FB22; HM89; LAP3; LCR1; NPYR; WHIM; CD184; LAP-3; LESTR; NPY3R; NPYRL; WHIMS; HSY3RR; NPYY3R; D2S201E
Swissprot P61073
Target Background
This gene encodes a CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to support HIV entry into cells and is also highly expressed in breast cancer cells. Mutations in this gene have been associated with WHIM (warts, hypogammaglobulinemia, infections, and myelokathexis) syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Anti-CXCR4 antibody Applications
Immunohistochemistry
Predicted cell location: Cell membrane
Positive control: Human liver cancer
Recommended dilution: 25-100 Predicted cell location: Cell membrane
Positive control: Human esophagus cancer
Recommended dilution: 25-100