Anti-FTH1 antibody

Anti-FTH1 antibody

Cat. No.     JLC220253
Package    25 μl/100 μl/200 μl
Storage    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Product overview
Description                   Anti-FTH1 rabbit polyclonal antibody
Applications        ELISA, IHC 
Immunogen               Fusion protein of human FTH1
Reactivity                 Human, Mouse, Rat
Content                     0.1 mg/ml
Host species               Rabbit
Ig class                  Immunogen-specific rabbit IgG
Purification                 Antigen affinity purification



Target information
Symbol                 FTH1
Full name                 Ferritin, heavy polypeptide 1
Synonyms    FHC, FTH, PLIF, FTHL6, PIG15
Swissprot    P02794

Target Background
This gene encodes the heavy subunit of ferritin, the major intracellular iron storage protein in prokaryotes and eukaryotes. It is composed of 24 subunits of the heavy and light ferritin chains. Variation in ferritin subunit composition may affect the rates of iron uptake and release in different tissues. A major function of ferritin is the storage of iron in a soluble and nontoxic state. Defects in ferritin proteins are associated with several neurodegenerative diseases. This gene has multiple pseudogenes. Several alternatively spliced transcript variants have been observed, but their biological validity has not been determined.