Product overview Description Anti-ARHGEF1 rabbit polyclonal antibody
Applications ELISA, IHC
Immunogen Fusion protein of human ARHGEF1
Reactivity Human, Mouse, Rat
Content 0.8 mg/ml
Host species Rabbit
Ig class Immunogen-specific rabbit IgG
Purification Antigen affinity purification
Target information Symbol ARHGEF1
Full name Rho guanine nucleotide exchange factor (GEF) 1
Synonyms LSC; GEF1; LBCL2; SUB1.5; P115-RHOGEF
Swissprot Q92888
Target Background Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form complex with G proteins and stimulate Rho-dependent signals. Multiple alternatively spliced transcript variants have been found for this gene, but the full-length nature of some variants has not been defined.
Applications Immunohistochemistry
Predicted cell location: Cytoplasm
Positive control: Human colon cancer
Recommended dilution: 100-300 Predicted cell location: Cytoplasm
Positive control: Human liver cancer
Recommended dilution: 100-300