Product overview
Description Anti-ACMSD rabbit polyclonal antibody
Applications ELISA, WB
Immunogen Fusion protein of human ACMSD
Reactivity Human, Mouse
Content 0.2 mg/ml
Host species Rabbit
Ig class Immunogen-specific rabbit IgG
Purification Antigen affinity purification
Anti-ACMSD antibody Target information
Symbol ACMSD
Full name Aminocarboxymuconate semialdehyde decarboxylase
Synonyms
Swissprot Q8TDX5
Target Background
The neuronal excitotoxin quinolinate is an intermediate in the de novo synthesis pathway of NAD from tryptophan, and has been implicated in the pathogenesis of several neurodegenerative disorders. Quinolinate is derived from alpha-amino-beta-carboxy-muconate-epsilon-semialdehyde (ACMS). ACMSD (ACMS decarboxylase; EC 4.1.1.45) can divert ACMS to a benign catabolite and thus prevent the accumulation of quinolinate from ACMS.
Anti-ACMSD antibody Applications
Western blotting
Predicted band size:38 kDa
Positive control:Raji cells
Recommended dilution: 500-2000