Product overview
Description Anti-APTX rabbit polyclonal antibody
Applications ELISA, IHC
Immunogen Fusion protein of human APTX
Reactivity Human, Mouse, Rat
Content 0.3 mg/ml
Host species Rabbit
Ig class Immunogen-specific rabbit IgG
Purification Antigen affinity purification
Target information
Symbol APTX
Full name aprataxin
Synonyms AOA; AOA1; AXA1; EAOH; EOAHA; FHA-HIT
Swissprot Q7Z2E3
Target Background
This gene encodes a member of the histidine triad (HIT) superfamily. The encoded protein may play a role in single-stranded DNA repair through its nucleotide-binding activity and its diadenosine polyphosphate hydrolase activity. Mutations in this gene have been associated with ataxia-ocular apraxia. Alternatively spliced transcript variants have been identified for this gene.