Product overview
Description Anti-IST1 rabbit polyclonal antibody
Applications ELISA, IHC
Immunogen Synthetic peptide of human IST1
Reactivity Human, Mouse, Rat
Content 1.08 mg/ml
Host species Rabbit
Ig class Immunogen-specific rabbit IgG
Purification Antigen affinity purification
Target information
Symbol IST1
Full name IST1, ESCRT-III associated factor
Synonyms OLC1
Swissprot P53990
Target Background
This gene encodes a protein with MIT-interacting motifs that interacts with components of endosomal sorting complexes required for transport (ESCRT). ESCRT functions in vesicle budding, such as that which occurs during membrane abscission in cytokinesis. There is a pseudogene for this gene on chromosome 19. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Applications
Immunohistochemistry
Predicted cell location: Cytoplasm and Nucleus
Positive control: Human colorectal cancer
Recommended dilution: 40-200 Predicted cell location: Cytoplasm and Nucleus
Positive control: Human tonsil
Recommended dilution: 40-200
The image on the left is immunohistochemistry of paraffin-embedded Human colorectal cancer tissue using ml264281(IST1 Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: ×200) The image on the left is immunohistochemistry of paraffin-embedded Human tonsil tissue using ml264281(IST1 Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: ×200)