Product overview
Description Anti-AES rabbit polyclonal antibody
Applications ELISA, IHC
Immunogen Fusion protein of human AES
Reactivity Human
Content 0.2 mg/ml
Host species Rabbit
Ig class Immunogen-specific rabbit IgG
Purification Antigen affinity purification
Target information
Symbol AES
Full name amino-terminal enhancer of split
Synonyms GRG; ESP1; GRG5; TLE5; AES-1; AES-2
Swissprot Q08117
Target Background
The protein encoded by this gene is similar in sequence to the amino terminus of Drosophila enhancer of split groucho, a protein involved in neurogenesis during embryonic development. The encoded protein, which belongs to the groucho/TLE family of proteins, can function as a homooligomer or as a heteroologimer with other family members to dominantly repress the expression of other family member genes. Three transcript variants encoding different isoforms have been found for this gene.