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- 详细信息
- 文献和实验
- 技术资料
- 供应商:
上海晶抗生物工程有限公司
- 库存:
大量
- 克隆性:
多克隆
- 保质期:
1年
- 抗体英文名:
Anti-TIMP1 antibody
- 宿主:
Rabbit
- 适应物种:
Human,Mouse,Rat,Chicken,Dog,Cow,Rabbit,Sheep
- 应用范围:
科研试验
- 保存条件:
-20°C
- 规格:
25 μl/100 μl/200 μl
Cat. No. JK121341
Package 25 μl/100 μl/200 μl
Storage -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Product overview
Description Anti-TIMP1 rabbit polyclonal antibody
Applications ELISA, IHC
Immunogen Fusion protein of human TIMP1
Reactivity Human
Content 0.1 mg/ml
Host species Rabbit
Ig class Immunogen-specific rabbit IgG
Purification Antigen affinity purification
Target information
Symbol TIMP1
Full name TIMP metallopeptidase inhibitor 1
Synonyms EPA; EPO; HCI; CLGI; TIMP
Swissprot P01033
Target Background
This gene belongs to the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases (MMPs), a group of peptidases involved in degradation of the extracellular matrix. In addition to its inhibitory role against most of the known MMPs, the encoded protein is able to promote cell proliferation in a wide range of cell types, and may also have an anti-apoptotic function. Transcription of this gene is highly inducible in response to many cytokines and hormones. In addition, the expression from some but not all inactive X chromosomes suggests that this gene inactivation is polymorphic in human females. This gene is located within intron 6 of the synapsin I gene and is transcribed in the opposite direction.
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