Product overview
Description Anti-PTGDR2 rabbit polyclonal antibody
Applications ELISA, WB, IHC
Immunogen Synthetic peptide of human PTGDR2
Reactivity Human, Mouse, Rat
Content 1.08 mg/ml
Host species Rabbit
Ig class Immunogen-specific rabbit IgG
Purification Antigen affinity purification
Target information
Symbol PTGDR2
Full name prostaglandin D2 receptor 2
Synonyms DP2; DL1R; CD294; CRTH2; GPR44
Swissprot Q9Y5Y4
Target Background
This gene encodes a G-protein-coupled receptor that is preferentially expressed in CD4+ effector T helper 2 (Th2) cells. This protein is a prostaglandin D2 receptor that mediates the pro-inflammatory chemotaxis of eosinophils, basophils, and Th2 lymphocytes generated during allergic inflammation. Single nucleotide polymorphisms in the 3' UTR of this gene have been associated with asthma susceptibility.
The image on the left is immunohistochemistry of paraffin-embedded Human tonsil tissue using ml264067(PTGDR2 Antibody) at dilution 1/35, on the right is treated with synthetic peptide. (Original magnification: ×200)
Western blotting
Predicted band size:43 kDa
Positive control:Human heart tissue lysate
Recommended dilution: 200-1000