Product overview
Description Anti-DUOX2 rabbit polyclonal antibody
Applications ELISA, IHC
Immunogen Synthetic peptide of human DUOX2
Reactivity Human, Rat
Content 0.6 mg/ml
Host species Rabbit
Ig class Immunogen-specific rabbit IgG
Purification Antigen affinity purification
Target information
Symbol DUOX2
Full name dual oxidase 2
Synonyms TDH6; LNOX2; THOX2; NOXEF2; P138-TOX
Swissprot Q9NRD8
Target Background
The protein encoded by this gene is a glycoprotein and a member of the NADPH oxidase family. The synthesis of thyroid hormone is catalyzed by a protein complex located at the apical membrane of thyroid follicular cells. This complex contains an iodide transporter, thyroperoxidase, and a peroxide generating system that includes this encoded protein and DUOX1. This protein is known as dual oxidase because it has both a peroxidase homology domain and a gp91phox domain.
Applications
Immunohistochemistry
Predicted cell location: Cell membrane
Positive control: Human brain
Recommended dilution: 20-100 Predicted cell location: Cell membrane
Positive control: Human esophagus cancer
Recommended dilution: 20-100
The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using ml263744(DUOX2 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: ×200) The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using ml263744(DUOX2 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: ×200)