Anti-DKK2 antibody

Anti-DKK2 antibody

Cat. No.     JK120557    
Package    25 μl/100 μl/200 μl
Storage    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Product overview
Description                   Anti-DKK2 rabbit polyclonal antibody
Applications        ELISA, IHC 
Immunogen               Fusion protein of human DKK2
Reactivity                 Human, Mouse
Content                     0.8 mg/ml
Host species               Rabbit
Ig class                  Immunogen-specific rabbit IgG
Purification                 Antigen affinity purification


Target information
Symbol                 DKK2
Full name                 dickkopf WNT signaling pathway inhibitor 2
Synonyms    DKK-2
Swissprot    Q9UBU2

Target Background
This gene encodes a protein that is a member of the dickkopf family. The secreted protein contains two cysteine rich regions and is involved in embryonic development through its interactions with the Wnt signaling pathway. It can act as either an agonist or antagonist of Wnt/beta-catenin signaling, depending on the cellular context and the presence of the co-factor kremen 2. Activity of this protein is also modulated by binding to the Wnt co-receptor LDL-receptor related protein 6 (LRP6).