Product overview
Description Anti-CYP1B1 rabbit polyclonal antibody
Applications ELISA, IHC
Immunogen Fusion protein of human CYP1B1
Reactivity Human, Mouse, Rat
Content 0.1 mg/ml
Host species Rabbit
Ig class Immunogen-specific rabbit IgG
Purification Antigen affinity purification
Target information
Symbol CYP1B1
Full name cytochrome P450, family 1, subfamily B, polypeptide 1
Synonyms CP1B; GLC3A; CYPIB1; P4501B1
Swissprot Q16678
Target Background
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The enzyme encoded by this gene localizes to the endoplasmic reticulum and metabolizes procarcinogens such as polycyclic aromatic hydrocarbons and 17beta-estradiol. Mutations in this gene have been associated with primary congenital glaucoma; therefore it is thought that the enzyme also metabolizes a signaling molecule involved in eye development, possibly a steroid.