Product overview
Description Anti-COX6C rabbit polyclonal antibody
Applications ELISA, WB
Immunogen Synthetic peptide of human COX6C
Reactivity Human, Mouse
Content 0.7 mg/ml
Host species Rabbit
Ig class Immunogen-specific rabbit IgG
Purification Antigen affinity purification
Target information
Symbol COX6C
Full name cytochrome c oxidase subunit 6C
Synonyms
Swissprot P09669
Target Background
Cytochrome c oxidase, the terminal enzyme of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. It is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may be involved in the regulation and assembly of the complex. This nuclear gene encodes subunit VIc, which has 77% amino acid sequence identity with mouse subunit VIc. This gene is up-regulated in prostate cancer cells. A pseudogene has been found on chromosomes 16p12.
Applications
Western blotting
Predicted band size:9 kDa
Positive control:Mouse heart tissue and Human heart tissue lysates
Recommended dilution: 500-2000