品牌:CST,产品名称:O-GlcNAc (CTD110.6) Mouse mAb (HRP Conjugate) #12938 英文名称:O-GlcNAc (CTD110.6) Mouse mAb (HRP Conjugate) Product name:O-GlcNAc (CTD110.6) Mouse mAb (HRP Conjugate) #12938 Applications:WB , Purification: Monoclonal antibody is produced by immunizing animals with a peptide containing serine-O-linked N-acetylglucosamine (O-GlcNAc). Background: O-GlcNAcylation is a post-translational modification where N-acetyl-D-glucosamine (GlcNAc) is covalently linked to cytoplasmic and nuclear proteins at serine or threonine residues (1,2). This modification is important in many cellular processes including metabolism, cell growth and morphogenesis, apoptosis and transcription (2,3) and has been implicated to play a critical role in cancer (1).
Specificity / Sensitivity:
O-GlcNAc (CTD110.6) Mouse mAb (HRP Conjugate) specifically recognizes endogenous levels of O-GlcNAc on proteins in β-O-glycosidic linkage to both serine and threonine.
Species Reactivity:
Human, Mouse, Rat, Monkey, All Species Expected
Application
Dilutions
Western Blotting
1:1000
Storage:
Supplied in 136 mM NaCl, 2.6 mM KCI, 12 mM sodium phosphate (pH 7.4) dibasic, 2 mg/ml BSA, and 50% glycerol. Store at –20°C. Do not aliquot the antibodies.
Product Description:
This Cell Signaling Technology® antibody is conjugated to the carbohydrate groups of horseradish peroxidase (HRP) via its amine groups. The HRP conjugated antibody is expected to exhibit the same species cross-reactivity as the unconjugated O-GlcNAc (CTD110.6) Mouse mAb #9875.