品牌:CST,产品名称:IP6K3 (D9O7J) Rabbit mAb #54322 英文名称:IP6K3 (D9O7J) Rabbit mAb Product name:IP6K3 (D9O7J) Rabbit mAb #54322 Source:Rabbit Sensitivity:Endogenous MW(kDa):32 Applications:WB , IP , Purification: Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Ala140 of human IP6K3 protein. Background: Inositol hexakisphosphate kinase 3 (IP6K3) is a member of the inositol hexakisphosphate kinase family (1). These kinases are essential for producing inositol pyrophosphates (1). IP6K3 is highly expressed in the cerebellar Purkinje cells, interacts with adducin and spectrin, and plays an important role in determining the cytoskeletal organization and function of these cells (1). In addition, the expression of IP6K3 increases upon treatment with titanium dioxide nanoparticles suggesting a role for IP6K3 in the genotoxicity caused by these nanoparticles (2).
IP6K3 (D9O7J) Rabbit mAb recognizes endogenous levels of total IP6K3 protein. This antibody does not cross-react with IP6K1 or IP6K2 proteins.
Species Reactivity:
Human
Application
Dilutions
Western Blotting
1:1000
Immunoprecipitation
1:50
Storage:
Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.