品牌:CST,产品名称:Ribosomal Protein S3 (D50G7) XP Rabbit mAb #9538 英文名称:Ribosomal Protein S3 (D50G7) XP® Rabbit mAb Product name:Ribosomal Protein S3 (D50G7) XP® Rabbit mAb #9538 Applications:WB , IP , IF , Purification: Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues near the amino terminus of human ribosomal protein S3. Background: Ribosomal protein S3 (rpS3) is a component of the 40S ribosomal subunit and is involved in translation. HSP90 interacts with both the amino-terminus and carboxy-terminus of rpS3, preventing its ubiquitination and degradation and thereby retaining the integrity of the ribosome (1). rpS3 has also been shown to function as an endonuclease during DNA damage repair (2,3). Furthermore, overexpression of rpS3 sensitizes lymphocytic cells to cytokine-induced apoptosis, indicating a third role for rpS3 during apoptosis (4). The functions of rpS3 during DNA damage repair and apoptosis have been mapped to two distinct domains (4).
Ribosomal Protein S3 (D50G7) XP® Rabbit mAb detects endogenous levels of total ribosomal protein S3.
Species Reactivity:
Human, Mouse, Rat, Monkey
Application
Dilutions
Western Blotting
1:1000
Immunoprecipitation
1:50
Immunofluorescence (Immunocytochemistry)
1:50
Storage:
Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.