品牌:CST,产品名称:PSD95 (7E3) Mouse mAb #36233 英文名称:PSD95 (7E3) Mouse mAb Product name:PSD95 (7E3) Mouse mAb #36233 Isotype:Rabbit IgG Sensitivity:Endogenous MW(kDa):95 Applications:WB , IF , Purification: Monoclonal antibody is produced by immunizing animals with recombinant protein specific to the full length rat PSD95 protein. Background: Postsynaptic Density protein 95 (PSD95) is a member of the membrane-associated guanylate kinase (MAGUK) family of proteins. These family members consist of an amino-terminal variable segment followed by three PDZ domains, a SH3 domain, and an inactive guanylate kinase (GK) domain. PSD95 is a scaffolding protein involved in the assembly and function of the postsynaptic density complex (1-2). PSD95 participates in synaptic targeting of AMPA receptors through an indirect manner involving Stargazin and related transmembrane AMPA receptor regulatory proteins (TARPs) (3). It is implicated in experience-dependent plasticity and plays an indispensable role in learning (4). Mutations in PSD95 are associated with autism (5).
PSD95 (7E3) Mouse mAb recognizes endogenous levels of total PSD95 protein.
Species Reactivity:
Human, Mouse, Rat
Application
Dilutions
Western Blotting
1:1000
Immunofluorescence (Frozen)
1:100
Immunofluorescence (Immunocytochemistry)
1:100
Storage:
Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.